ENTRIL 20 ORAL

entril-20-oralFOR POULTRY

PRESENTATION: 

A ready to use clear aqueous oral solution containing 200 mg/ml enrofloxacin.

USES:
Enrofloxacin is a synthetic, broad spectrum antimicrobial, bactericidal in action and effective against a wide range of gram positive and gram negative bacteria as well as mycoplasmas.  It is indicated for use in Turkeys, Broilers, Broiler breeders, and Replacement Chickens, for diseases of the respiratory and alimentary tract, of bacterial or mycoplasmal origin, e.g. pasteurellosis, mycoplasmosis, coli-bacillosis, coli-septicaemia and salmonellosis, where clinical experience, supported where possible by sensitivity testing of the causal organism, indicates enrofloxacin as the drug of choice.

DOSAGE AND ADMINISTRATION:
ENTRIL 20 ORAL is administered via the drinking water.

  • Medicated water should be made up immediately prior to administration.
  • Medication of the water supply should be continuous during the treatment period and no other source of water should be available.
  • The dose rate is 10 mg per kg bodyweight, daily for 3 to 10 days.  Carefully calculate the total body mass to be treated and the total daily water consumption.  Under normal conditions 0.25 ml / litre (50 ppm) is sufficient.  Mature birds such as breeders may require 0.50 ml / litre (100 ppm)
  • ENTRIL 20 ORAL may be put directly into the header tank or introduced via a water proportioner pump.
  • For the treatment of salmonellosis or pasteurellosis a treatment period of 5 to 10 days must be used.  For other conditions the duration of treatment may be 3 to 5 days.

CONTRA-INDICATIONS, WARNINGS ETC:

For animal treatment only.

KEEP OUT OF THE REACH OF CHILDREN.
Do not exceed the recommended dose.
Wear impervious gloves when handling the product.
Wash any splashes from skin or eyes immediately with water.
Wash hands and exposed skin after use.
Do not eat, drink, or smoke whilst using the product.
Do not use in poultry producing eggs for human consumption.
Do not administer to replacement birds within 14 days of coming into lay.

WITHDRAWAL PERIOD:
Birds must not be slaughtered for human consumption during treatment or for 8 days following withdrawal of treatment.

PHARMACEUTICAL PRECAUTIONS:
Store below 25 degrees Centigrade in a dry place away from food.
Following withdrawal of the first dose, use the product within 28 days.
Discard unused material.
Medicated water should be made up on a daily basis.  Any medicated water remaining after 24 hours must be discarded.

PACKAGE QUANTITIES:
100 ml, 250 ml, 500 ml, and 1 litre plastic bottles.

FURTHER INFORMATION:
The pharmacokinetics of enrofloxacin are such that both oral and parenteral administration lead to similar serum levels.  Enrofloxacin possesses a high distribution volume.  Tissue levels 2-3 times higher than that found in the serum have been demonstrated in laboratory animals and target species.  Organs in which high levels cab be expected are the lungs, liver, kidney, bone, and lymphatic system. Enrofloxacin also distributes into the C.S.F., the aqueous humour, and the foetus in pregnant animals.